This domain of our applications will be based on mathematical models as developed in collaboration with nationally renowned experts in the field with continued development of pharmacokinetic models that consider individualized dosing strategies.
Meet the PK team
University of Pennsylvania Philadelphia, PA
Raymod C. Boston, B.Sc., M.Sc, Ph.D. is a Member of the Abramson Cancer Center of the School of Medicine, University of Pennsylvania, Senior Scholar, Center for Clinical Epidemiology and Biostatistics (CCEB), Perelman School of Medicine, University of Pennsylvania, Professor Emeritus of Applied Biomathematics, School of Veterinary Medicine, University of Pennsylvania, and Professor Emeritus of Biostatistics, Department of Biostatistics and Epidemiology, Perelman School of Medicine School of Medicine, University of Pennsylvania. Dr.Boston has published numerous book chapters and has over 325 publications in peer-reviewed scientific journals. He is well known for his development of the NIHWinSAAM software in collaboration with Dr. Peter C. Grief, and his authorship of the book Investigating Biological Systems using Modeling: Strategies and Software.
Dr. Linares graduated from Eastern Central University Medical School, on the border with Haiti, in 1981. After internal medicine residency, he completed fellowship training in geriatric medicine and gerontology at the University of Michigan, Ann Arbor. He was lecturer at the University of Michigan Medical School. Dr. Linares served the Division of Geriatric Medicine under the guidance of Professor Jeffrey B. Halter, MD. He was Visiting Fellow through 2000 and Visiting Scholar in mathematical and molecular medicine, University of Michigan Horace H. Rackham School of Graduate Studies 2001-2003. Dr. Linares studied mathematical medicine under Dr. Loren A Zech, Senior Scientist, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD. Dr. Linares’ research interests include neural regulation of sympathetic nervous system activity in pain states, the microcirculation, mass transport, population PK/PD modeling and pharmacogenomics (PGx) for opioid dose regimen design in general, and gerontokinetics in particular. Dr. Linares has been working on novel applications of PK/PD-PGx for patient safety. He is an author of many research papers, several book chapters and is a co-author of the 1st edition of Investigating Biological Systems using Modeling published by Academic Press 2000. He has been a member of several national pain organizations including the American Pain Society, where he was Chair of the Geriatric Pain SIG (2009-2011). He was elected to membership in the Interamerican College of Physicians and Surgeons, and Fellow of the Interamerican College Physicians and Surgeons. Dr. Linares is a recipient of the Great Seal of the United States presented by Congressman John Dingell (DMichigan) for his research on ageing. It is the highest honor bestowed on a citizen by the State of Michigan. He also received a letter of congratulation for scholarship from Dr. Jack Rowe, Division on Aging, Harvard Medical School, for his work on sympathochromaffin system function in the elderly. Dr. Linares sings baritone for the Chancel Choir, Plymouth First United Methodist Church. Dr. Linares is a voice for black people enslaved by pain in the United States.
WILLIAM E. SCHIESSER is Emeritus McCann Professor of Chemical and Biomolecular Engineering and Professor of Mathematics at Lehigh University. He holds a PhD from Princeton University and an ScD (hon) from the University of Mons, Belgium. His research is directed toward numerical methods and associated software for ordinary, differential-algebraic and partial differential equations (ODE/DAE/PDEs), and the development of mathematical models based on ODE/DAE/PDEs. He is the author or coauthor of 14 books, and his ODE/DAE/PDE computer routines have been accessed by some 5,000 colleges and universities, corporations and government agencies.
ANNEMARIE L. DALY, M.D., J.D., F.A.C.P., H.M.D.C., is a graduate of the University of Michigan Medical School, Ann Arbor. Dr. Daly completed internship in psychiatry